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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2C
All Species:
21.21
Human Site:
S324
Identified Species:
38.89
UniProt:
Q06413
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06413
NP_002388.2
473
51221
S324
T
T
Y
G
T
E
Y
S
L
S
S
A
D
L
S
Chimpanzee
Pan troglodytes
XP_001139828
503
54271
S354
S
A
L
Q
G
F
N
S
P
G
M
L
S
L
G
Rhesus Macaque
Macaca mulatta
XP_001086412
483
52310
S334
T
T
Y
G
T
E
Y
S
L
S
S
A
D
L
S
Dog
Lupus familis
XP_858441
472
51065
S323
T
T
Y
G
T
E
Y
S
L
S
S
A
D
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFN5
474
51260
S324
T
T
Y
G
T
E
Y
S
L
S
S
A
D
L
S
Rat
Rattus norvegicus
Q2MJT0
495
53235
T346
L
S
A
L
Q
G
F
T
S
P
G
M
L
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510456
503
54885
S354
T
T
Y
G
T
E
Y
S
L
S
S
A
D
L
S
Chicken
Gallus gallus
Q9W6U8
499
53650
E350
S
A
D
L
S
A
F
E
G
F
N
S
P
G
M
Frog
Xenopus laevis
Q03413
498
54053
Q339
T
A
Y
N
T
D
Y
Q
L
T
S
A
D
L
A
Zebra Danio
Brachydanio rerio
NP_571387
465
49956
L315
S
Y
G
T
E
Y
S
L
S
S
G
D
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
N372
S
G
H
Q
Q
N
S
N
G
S
T
G
S
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
S119
L
T
F
K
E
L
Q
S
L
E
Q
Q
L
Y
H
Baker's Yeast
Sacchar. cerevisiae
P38128
452
49396
L304
T
V
A
I
S
N
T
L
E
G
P
A
P
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.4
93.3
99.1
N.A.
98.7
56.5
N.A.
93
63.1
56.6
79.4
N.A.
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
74.3
94.8
99.3
N.A.
99.7
69.2
N.A.
94
74.1
70.4
88.5
N.A.
50
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
0
N.A.
100
0
60
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
100
33.3
80
20
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
16
0
0
8
0
0
0
0
0
54
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
0
0
8
47
0
0
% D
% Glu:
0
0
0
0
16
39
0
8
8
8
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
8
16
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
8
39
8
8
0
0
16
16
16
8
0
16
16
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
0
8
16
0
8
0
16
54
0
0
8
24
54
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% M
% Asn:
0
0
0
8
0
16
8
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
8
8
0
16
0
0
% P
% Gln:
0
0
0
16
16
0
8
8
0
0
8
8
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
31
8
0
0
16
0
16
54
16
54
47
8
16
16
47
% S
% Thr:
54
47
0
8
47
0
8
8
0
8
8
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
47
0
0
8
47
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _